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Predicting continuous local structure and the effect of its substitution for secondary structure in fragment-free protein structure prediction

Local structures predicted from protein sequences are employed extensively in every aspect of modeling and prediction of protein structure and function. For more than 50 years, they have been predicted at a low-resolution coarse-grained level (e.g. three-state secondary structure). Here, we combine...

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Main Authors: Faraggi, Eshel, Yang, Yuedong, Zhang, Shesheng, Zhou, Yaoqi
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778607/
https://ncbi.nlm.nih.gov/pubmed/19913486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.09.006
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