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Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an essential process that provides nutrients and oxygen to the nascent tumor and thereby enhances tumor-cell survival and facilitates grow...

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Detalles Bibliográficos
Autores principales: Fernández, Jaime G, Rodríguez, Diego A, Valenzuela, Manuel, Calderon, Claudia, Urzúa, Ulises, Munroe, David, Rosas, Carlos, Lemus, David, Díaz, Natalia, Wright, Mathew C, Leyton, Lisette, Tapia, Julio C, Quest, Andrew FG
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177250/
https://ncbi.nlm.nih.gov/pubmed/25204429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-209
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