Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an essential process that provides nutrients and oxygen to the nascent tumor and thereby enhances tumor-cell survival and facilitates grow...

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Detalhes bibliográficos
Main Authors: Fernández, Jaime G, Rodríguez, Diego A, Valenzuela, Manuel, Calderon, Claudia, Urzúa, Ulises, Munroe, David, Rosas, Carlos, Lemus, David, Díaz, Natalia, Wright, Mathew C, Leyton, Lisette, Tapia, Julio C, Quest, Andrew FG
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177250/
https://ncbi.nlm.nih.gov/pubmed/25204429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-209
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