Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an essential process that provides nutrients and oxygen to the nascent tumor and thereby enhances tumor-cell survival and facilitates grow...

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Autors principals: Fernández, Jaime G, Rodríguez, Diego A, Valenzuela, Manuel, Calderon, Claudia, Urzúa, Ulises, Munroe, David, Rosas, Carlos, Lemus, David, Díaz, Natalia, Wright, Mathew C, Leyton, Lisette, Tapia, Julio C, Quest, Andrew FG
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177250/
https://ncbi.nlm.nih.gov/pubmed/25204429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-209
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