Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription

Early in cancer development, tumour cells express vascular endothelial growth factor (VEGF), a secreted molecule that is important in all stages of angiogenesis, an essential process that provides nutrients and oxygen to the nascent tumor and thereby enhances tumor-cell survival and facilitates grow...

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Dettagli Bibliografici
Autori principali: Fernández, Jaime G, Rodríguez, Diego A, Valenzuela, Manuel, Calderon, Claudia, Urzúa, Ulises, Munroe, David, Rosas, Carlos, Lemus, David, Díaz, Natalia, Wright, Mathew C, Leyton, Lisette, Tapia, Julio C, Quest, Andrew FG
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177250/
https://ncbi.nlm.nih.gov/pubmed/25204429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-209
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