Life extension factor klotho enhances cognition

Aging is the primary risk factor for cognitive decline, an emerging health threat to aging societies worldwide. Whether anti-aging factors such as klotho can counteract cognitive decline is unknown. We show that a life span-extending variant of the human KLOTHO gene, KL-VS, is associated with enhanc...

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Detalhes bibliográficos
Main Authors: Dubal, Dena B., Yokoyama, Jennifer S., Zhu, Lei, Broestl, Lauren, Worden, Kurtresha, Wang, Dan, Sturm, Virginia E., Kim, Daniel, Klein, Eric, Yu, Gui-Qiu, Ho, Kaitlyn, Eilertson, Kirsten E., Yu, Lei, Kuro-o, Makoto, De Jager, Philip L., Coppola, Giovanni, Small, Gary W., Bennett, David A., Kramer, Joel H., Abraham, Carmela R., Miller, Bruce L., Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176932/
https://ncbi.nlm.nih.gov/pubmed/24813892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.076
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