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Klotho controls the brain–immune system interface in the choroid plexus

Located within the brain’s ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood. For unknown reasons, the choroid plexus produces high levels of the protein klotho. Here, we show that these levels naturally declin...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhu, Lei, Stein, Liana R., Kim, Daniel, Ho, Kaitlyn, Yu, Gui-Qiu, Zhan, Lihong, Larsson, Tobias E., Mucke, Lennart
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275534/
https://ncbi.nlm.nih.gov/pubmed/30413620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808609115
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