Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery

The RNA component of signal recognition particle (SRP) is transcribed by RNA polymerase III, and most steps in SRP biogenesis occur in the nucleolus. Here, we examine processing and quality control of the yeast SRP RNA (scR1). In common with other pol III transcripts, scR1 terminates in a U-tract, a...

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Bibliographic Details
Main Authors: Leung, Eileen, Schneider, Claudia, Yan, Fu, Mohi-El-Din, Hatem, Kudla, Grzegorz, Tuck, Alex, Wlotzka, Wiebke, Doronina, Victoria A., Bartley, Ralph, Watkins, Nicholas J., Tollervey, David, Brown, Jeremy D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176351/
https://ncbi.nlm.nih.gov/pubmed/25159613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku761
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