The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans

During ribosomal RNA (rRNA) maturation, cleavages at defined sites separate the mature rRNAs from spacer regions, but the identities of several enzymes required for 18S rRNA release remain unknown. PilT N-terminus (PIN) domain proteins are frequently endonucleases and the PIN domain protein Utp24 is...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Wells, Graeme R., Weichmann, Franziska, Colvin, David, Sloan, Katherine E., Kudla, Grzegorz, Tollervey, David, Watkins, Nicholas J., Schneider, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914098/
https://ncbi.nlm.nih.gov/pubmed/27034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw213
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