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The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans

During ribosomal RNA (rRNA) maturation, cleavages at defined sites separate the mature rRNAs from spacer regions, but the identities of several enzymes required for 18S rRNA release remain unknown. PilT N-terminus (PIN) domain proteins are frequently endonucleases and the PIN domain protein Utp24 is...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wells, Graeme R., Weichmann, Franziska, Colvin, David, Sloan, Katherine E., Kudla, Grzegorz, Tollervey, David, Watkins, Nicholas J., Schneider, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914098/
https://ncbi.nlm.nih.gov/pubmed/27034467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw213
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