The ribosome biogenesis factor yUtp23/hUTP23 coordinates key interactions in the yeast and human pre-40S particle and hUTP23 contains an essential PIN domain

Two proteins with PIN endonuclease domains, yUtp24(Fcf1)/hUTP24 and yUtp23/hUTP23 are essential for early pre-ribosomal (r)RNA cleavages at sites A0, A1/1 and A2/2a in yeast and humans. The yUtp24/hUTP24 PIN endonuclease is proposed to cleave at sites A1/1 and A2/2a, but the enzyme cleaving at site...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wells, Graeme R., Weichmann, Franziska, Sloan, Katherine E., Colvin, David, Watkins, Nicholas J., Schneider, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5416842/
https://ncbi.nlm.nih.gov/pubmed/28082392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1344
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