Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site

The polymerization of amino acids into proteins occurs on ribosomes, with the rate influenced by the amino acids being polymerized. The imino acid proline is a poor donor and acceptor for peptide-bond formation, such that translational stalling occurs when three or more consecutive prolines (PPP) ar...

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Bibliographic Details
Main Authors: Starosta, Agata L., Lassak, Jürgen, Peil, Lauri, Atkinson, Gemma C., Virumäe, Kai, Tenson, Tanel, Remme, Jaanus, Jung, Kirsten, Wilson, Daniel N.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176338/
https://ncbi.nlm.nih.gov/pubmed/25143529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku768
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