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Evolutionary analysis of polyproline motifs in Escherichia coli reveals their regulatory role in translation

Translation of consecutive prolines causes ribosome stalling, which is alleviated but cannot be fully compensated by the elongation factor P. However, the presence of polyproline motifs in about one third of the E. coli proteins underlines their potential functional importance, which remains largely...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Qi, Fei, Motz, Magdalena, Jung, Kirsten, Lassak, Jürgen, Frishman, Dmitrij
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811046/
https://ncbi.nlm.nih.gov/pubmed/29389943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005987
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