A conserved proline triplet in Val-tRNA synthetase and the origin of elongation factor P

Bacterial ribosomes stall on polyproline stretches and require the elongation factor P (EF-P) to relieve the arrest. Yet it remains unclear why evolution has favored the development of EF-P, rather than selecting against the occurrence of polyproline stretches in proteins. We have discovered that on...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Starosta, Agata L., Lassak, Jürgen, Peil, Lauri, Atkinson, Gemma C., Woolstenhulme, Christopher J., Virumäe, Kai, Buskirk, Allen, Tenson, Tanel, Remme, Jaanus, Jung, Kirsten, Wilson, Daniel N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847715/
https://ncbi.nlm.nih.gov/pubmed/25310979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.008
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