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Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P
Ribosomes are the protein synthesizing factories of the cell, polymerizing polypeptide chains from their constituent amino acids. However, distinct combinations of amino acids, such as polyproline stretches, cannot be efficiently polymerized by ribosomes, leading to translational stalling. The stall...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780873/ https://ncbi.nlm.nih.gov/pubmed/24003132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310642110 |
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