Distinct XPPX sequence motifs induce ribosome stalling, which is rescued by the translation elongation factor EF-P

Ribosomes are the protein synthesizing factories of the cell, polymerizing polypeptide chains from their constituent amino acids. However, distinct combinations of amino acids, such as polyproline stretches, cannot be efficiently polymerized by ribosomes, leading to translational stalling. The stall...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peil, Lauri, Starosta, Agata L., Lassak, Jürgen, Atkinson, Gemma C., Virumäe, Kai, Spitzer, Michaela, Tenson, Tanel, Jung, Kirsten, Remme, Jaanus, Wilson, Daniel N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780873/
https://ncbi.nlm.nih.gov/pubmed/24003132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310642110
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