ロード中...
Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci
Expression of the L1 retrotransposon can damage the genome through insertional mutagenesis and the generation of DNA double-strand breaks (DSBs). The majority of L1 loci in the human genome are 5′-truncated and therefore incapable of retrotransposition. While thousands of full-length L1 loci remain,...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176336/ https://ncbi.nlm.nih.gov/pubmed/25143528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku687 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|