Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1

The enzymatic processing of cellular RNA molecules requires selective recognition of unique chemical and topological features. The unusual 2′,5′-phosphodiester linkages in RNA lariats produced by the spliceosome must be hydrolyzed by the intron debranching enzyme (Dbr1) before they can be metabolize...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Montemayor, Eric J., Katolik, Adam, Clark, Nathaniel E., Taylor, Alexander B., Schuermann, Jonathan P., Combs, D. Joshua, Johnsson, Richard, Holloway, Stephen P., Stevens, Scott W., Damha, Masad J., Hart, P. John
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176325/
https://ncbi.nlm.nih.gov/pubmed/25123664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku725
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