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Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1
The enzymatic processing of cellular RNA molecules requires selective recognition of unique chemical and topological features. The unusual 2′,5′-phosphodiester linkages in RNA lariats produced by the spliceosome must be hydrolyzed by the intron debranching enzyme (Dbr1) before they can be metabolize...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176325/ https://ncbi.nlm.nih.gov/pubmed/25123664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku725 |
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