The Spatiotemporal Dynamics of Chromatin Protein HP1α Is Essential for Accurate Chromosome Segregation during Cell Division

Heterochromatin protein 1α (HP1α) is involved in regulation of chromatin plasticity, DNA damage repair, and centromere dynamics. HP1α detects histone dimethylation and trimethylation of Lys-9 via its chromodomain. HP1α localizes to heterochromatin in interphase cells but is liberated from chromosoma...

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Autors principals: Chu, Lingluo, Huo, Yuda, Liu, Xing, Yao, Phil, Thomas, Kelwyn, Jiang, Hao, Zhu, Tongge, Zhang, Guanglan, Chaudhry, Maryam, Adams, Gregory, Thompson, Winston, Dou, Zhen, Jin, Changjiang, He, Ping, Yao, Xuebiao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176231/
https://ncbi.nlm.nih.gov/pubmed/25104354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.581504
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