Chromatin Protein HP1α Interacts with the Mitotic Regulator Borealin Protein and Specifies the Centromere Localization of the Chromosomal Passenger Complex

Accurate mitosis requires the chromosomal passenger protein complex (CPC) containing Aurora B kinase, borealin, INCENP, and survivin, which orchestrates chromosome dynamics. However, the chromatin factors that specify the CPC to the centromere remain elusive. Here we show that borealin interacts dir...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Xing, Song, Zhenwei, Huo, Yuda, Zhang, Jiahai, Zhu, Tongge, Wang, Jianyu, Zhao, Xuannv, Aikhionbare, Felix, Zhang, Jiancun, Duan, Hequan, Wu, Jihui, Dou, Zhen, Shi, Yunyu, Yao, Xuebiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110276/
https://ncbi.nlm.nih.gov/pubmed/24917673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572842
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