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Chromatin Protein HP1α Interacts with the Mitotic Regulator Borealin Protein and Specifies the Centromere Localization of the Chromosomal Passenger Complex

Accurate mitosis requires the chromosomal passenger protein complex (CPC) containing Aurora B kinase, borealin, INCENP, and survivin, which orchestrates chromosome dynamics. However, the chromatin factors that specify the CPC to the centromere remain elusive. Here we show that borealin interacts dir...

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Autors principals: Liu, Xing, Song, Zhenwei, Huo, Yuda, Zhang, Jiahai, Zhu, Tongge, Wang, Jianyu, Zhao, Xuannv, Aikhionbare, Felix, Zhang, Jiancun, Duan, Hequan, Wu, Jihui, Dou, Zhen, Shi, Yunyu, Yao, Xuebiao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110276/
https://ncbi.nlm.nih.gov/pubmed/24917673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572842
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