Chromatin Protein HP1α Interacts with the Mitotic Regulator Borealin Protein and Specifies the Centromere Localization of the Chromosomal Passenger Complex

Accurate mitosis requires the chromosomal passenger protein complex (CPC) containing Aurora B kinase, borealin, INCENP, and survivin, which orchestrates chromosome dynamics. However, the chromatin factors that specify the CPC to the centromere remain elusive. Here we show that borealin interacts dir...

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Hlavní autoři: Liu, Xing, Song, Zhenwei, Huo, Yuda, Zhang, Jiahai, Zhu, Tongge, Wang, Jianyu, Zhao, Xuannv, Aikhionbare, Felix, Zhang, Jiancun, Duan, Hequan, Wu, Jihui, Dou, Zhen, Shi, Yunyu, Yao, Xuebiao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110276/
https://ncbi.nlm.nih.gov/pubmed/24917673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572842
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