Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation

Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules. The microtubule depolymerase mitotic centromere-associated kinesin (MCAK) is a key regulator for an accurate kinetochore-microtubule attachment. However, the regulatory mec...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Shao, Hengyi, Huang, Yuejia, Zhang, Liangyu, Yuan, Kai, Chu, Youjun, Dou, Zhen, Jin, Changjiang, Garcia-Barrio, Minerva, Liu, Xing, Yao, Xuebiao
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513279/
https://ncbi.nlm.nih.gov/pubmed/26206521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12204
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items