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An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4

The tumor suppressor protein programmed cell death 4 (Pdcd4) has been implicated in the translational regulation of specific mRNAs, however, the identities of the natural Pdcd4 target mRNAs and the mechanisms by which Pdcd4 affects their translation are not well understood. Pdcd4 binds to the eukary...

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Autors principals: Fehler, Olesja, Singh, Priyanka, Haas, Astrid, Ulrich, Diana, Müller, Jan P., Ohnheiser, Johanna, Klempnauer, Karl-Heinz
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176178/
https://ncbi.nlm.nih.gov/pubmed/25190455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku800
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