Regulatory interactions maintaining self-renewal of human embryonic stem cells as revealed through a systems analysis of PI3K/AKT pathway

Motivation: Maintenance of the self-renewal state in human embryonic stem cells (hESCs) is the foremost critical step for regenerative therapy applications. The insulin-mediated PI3K/AKT pathway is well appreciated as being the central pathway supporting hESC self-renewal; however, the regulatory in...

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Detaylı Bibliyografya
Asıl Yazarlar: Mathew, Shibin, Sundararaj, Sankaramanivel, Mamiya, Hikaru, Banerjee, Ipsita
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2014
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176056/
https://ncbi.nlm.nih.gov/pubmed/24778109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu209
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