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Quantitative Analysis of Robustness of Dynamic Response and Signal Transfer in Insulin mediated PI3K/AKT Pathway

Robustness is a critical feature of signaling pathways ensuring signal propagation with high fidelity in the event of perturbations. Here we present a detailed quantitative analysis of robustness in insulin mediated PI3K/AKT pathway, a critical signaling pathway maintaining self-renewal in human emb...

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Detalhes bibliográficos
Publicado no:Comput Chem Eng
Main Authors: Mathew, Shibin, Banerjee, Ipsita
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261235/
https://ncbi.nlm.nih.gov/pubmed/25506104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compchemeng.2014.07.018
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