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Mother-daughter asymmetry of pH underlies aging and rejuvenation in yeast
Replicative aging in yeast is asymmetric–mother cells age but their daughter cells are rejuvenated. Here we identify an asymmetry in pH between mother and daughter cells that underlies aging and rejuvenation. Cytosolic pH increases in aging mother cells, but is more acidic in daughter cells. This is...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175738/ https://ncbi.nlm.nih.gov/pubmed/25190112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03504 |
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