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The landscape of kinase fusions in cancer

Human cancer genomes harbour a variety of alterations leading to the deregulation of key pathways in tumour cells. The genomic characterization of tumours has uncovered numerous genes recurrently mutated, deleted or amplified, but gene fusions have not been characterized as extensively. Here we deve...

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Hlavní autoři: Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175590/
https://ncbi.nlm.nih.gov/pubmed/25204415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5846
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