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A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory

Histone deacetylases (HDACs) are a family of chromatin remodeling enzymes that restrict access of transcription factors to the DNA, thereby repressing gene expression. In contrast, histone acetyltransferases (HATs) relax the chromatin structure allowing for an active chromatin state and promoting ge...

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Detalles Bibliográficos
Autores principales: Mahgoub, Melissa, Monteggia, Lisa M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175496/
https://ncbi.nlm.nih.gov/pubmed/25227251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.036012.114
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