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A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory

Histone deacetylases (HDACs) are a family of chromatin remodeling enzymes that restrict access of transcription factors to the DNA, thereby repressing gene expression. In contrast, histone acetyltransferases (HATs) relax the chromatin structure allowing for an active chromatin state and promoting ge...

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Bibliografski detalji
Glavni autori: Mahgoub, Melissa, Monteggia, Lisa M.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175496/
https://ncbi.nlm.nih.gov/pubmed/25227251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.036012.114
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