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Loss of Histone Deacetylase 2 Improves Working Memory and Accelerates Extinction Learning

Histone acetylation and deacetylation can be dynamically regulated in response to environmental stimuli and play important roles in learning and memory. Pharmacological inhibition of histone deacetylases (HDACs) improves performance in learning tasks; however, many of these classical agents are “pan...

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Detalhes bibliográficos
Main Authors: Morris, Michael J., Mahgoub, Melissa, Na, Elisa S., Pranav, Heena, Monteggia, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773986/
https://ncbi.nlm.nih.gov/pubmed/23575838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1001-12.2013
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