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A role for histone deacetylases in the cellular and behavioral mechanisms underlying learning and memory
Histone deacetylases (HDACs) are a family of chromatin remodeling enzymes that restrict access of transcription factors to the DNA, thereby repressing gene expression. In contrast, histone acetyltransferases (HATs) relax the chromatin structure allowing for an active chromatin state and promoting ge...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175496/ https://ncbi.nlm.nih.gov/pubmed/25227251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.036012.114 |
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