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Safety Assessment of Liver-Targeted Hydrodynamic Gene Delivery in Dogs

Evidence in support of safety of a gene delivery procedure is essential toward gene therapy. Previous studies using the hydrodynamics-based procedure primarily focus on gene delivery efficiency or gene function analysis in mice. The current study focuses on an assessment of the safety of computer-co...

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Detalhes bibliográficos
Main Authors: Kamimura, Kenya, Kanefuji, Tsutomu, Yokoo, Takeshi, Abe, Hiroyuki, Suda, Takeshi, Kobayashi, Yuji, Zhang, Guisheng, Aoyagi, Yutaka, Liu, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175463/
https://ncbi.nlm.nih.gov/pubmed/25251246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107203
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