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Parameters Affecting Image-guided, Hydrodynamic Gene Delivery to Swine Liver

Development of a safe and effective method for gene delivery to hepatocytes is a critical step toward gene therapy for liver diseases. Here, we assessed the parameters for gene delivery to the livers of large animals (pigs, 40–65 kg) using an image-guided hydrodynamics-based procedure that involves...

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Detalhes bibliográficos
Main Authors: Kamimura, Kenya, Suda, Takeshi, Zhang, Guisheng, Aoyagi, Yutaka, Liu, Dexi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027427/
https://ncbi.nlm.nih.gov/pubmed/24129227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2013.52
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