Effects of Fibrotic Tissue on Liver-targeted Hydrodynamic Gene Delivery

Hydrodynamic gene delivery is a common method for gene transfer to the liver of small animals, and its clinical applicability in large animals has been demonstrated. Previous studies focused on functional analyses of therapeutic genes in animals with normal livers and little, however, is known regar...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Kobayashi, Yuji, Kamimura, Kenya, Abe, Hiroyuki, Yokoo, Takeshi, Ogawa, Kohei, Shinagawa-Kobayashi, Yoko, Goto, Ryo, Inoue, Ryosuke, Ohtsuka, Masato, Miura, Hiromi, Kanefuji, Tsutomu, Suda, Takeshi, Tsuchida, Masanori, Aoyagi, Yutaka, Zhang, Guisheng, Liu, Dexi, Terai, Shuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023407/
https://ncbi.nlm.nih.gov/pubmed/27574785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.63
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