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Cytosine Deamination is a Major Cause of Baseline Noise in Next Generation Sequencing
BACKGROUND AND OBJECTIVES: As next generation sequencing (NGS) becomes a major sequencing platform in clinical diagnostic laboratories, it is critical to identify artifacts that constitute baseline noise and may interfere with detection of low level gene mutations. This is especially critical for ap...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175022/ https://ncbi.nlm.nih.gov/pubmed/25091469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40291-014-0115-2 |
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