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Multimerization Domains are Associated with Apparent Strand Exchange Activity in BLM and WRN DNA helicases

BLM and WRN are members of the RecQ family of DNA helicases that act to suppress genome instability and cancer predisposition. In addition to a RecQ helicase domain, each of these proteins contains an N-terminal domain of approximately 500 amino acids (aa) that is incompletely characterized. Previou...

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Detalhes bibliográficos
Main Authors: Chen, Chi-Fu, Brill, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174979/
https://ncbi.nlm.nih.gov/pubmed/25198671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.07.015
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