Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functi...

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書誌詳細
主要な著者: Lee, Ho-Hsien, Cherni, Irene, Yu, HongQi, Fromme, Raimund, Doran, Jeffrey D., Grotjohann, Ingo, Mittman, Michele, Basu, Shibom, Deb, Arpan, Dörner, Katerina, Aquila, Andrew, Barty, Anton, Boutet, Sébastien, Chapman, Henry N., Doak, R. Bruce, Hunter, Mark S., James, Daniel, Kirian, Richard A., Kupitz, Christopher, Lawrence, Robert M., Liu, Haiguang, Nass, Karol, Schlichting, Ilme, Schmidt, Kevin E., Seibert, M. Marvin, Shoeman, Robert L., Spence, John C. H., Stellato, Francesco, Weierstall, Uwe, Williams, Garth J., Yoon, Chunhong, Wang, Dingjie, Zatsepin, Nadia A., Hogue, Brenda G., Matoba, Nobuyuki, Fromme, Petra, Mor, Tsafrir S.
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2014
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174873/
https://ncbi.nlm.nih.gov/pubmed/25295172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252514014900
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