Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1

CTB-MPR is a fusion protein between the B subunit of cholera toxin (CTB) and the membrane-proximal region of gp41 (MPR), the transmembrane envelope protein of Human immunodeficiency virus 1 (HIV-1), and has previously been shown to induce the production of anti-HIV-1 antibodies with antiviral functi...

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Detalhes bibliográficos
Main Authors: Lee, Ho-Hsien, Cherni, Irene, Yu, HongQi, Fromme, Raimund, Doran, Jeffrey D., Grotjohann, Ingo, Mittman, Michele, Basu, Shibom, Deb, Arpan, Dörner, Katerina, Aquila, Andrew, Barty, Anton, Boutet, Sébastien, Chapman, Henry N., Doak, R. Bruce, Hunter, Mark S., James, Daniel, Kirian, Richard A., Kupitz, Christopher, Lawrence, Robert M., Liu, Haiguang, Nass, Karol, Schlichting, Ilme, Schmidt, Kevin E., Seibert, M. Marvin, Shoeman, Robert L., Spence, John C. H., Stellato, Francesco, Weierstall, Uwe, Williams, Garth J., Yoon, Chunhong, Wang, Dingjie, Zatsepin, Nadia A., Hogue, Brenda G., Matoba, Nobuyuki, Fromme, Petra, Mor, Tsafrir S.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174873/
https://ncbi.nlm.nih.gov/pubmed/25295172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252514014900
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