Accurate Identification of ALK Positive Lung Carcinoma Patients: Novel FDA-Cleared Automated Fluorescence In Situ Hybridization Scanning System and Ultrasensitive Immunohistochemistry

BACKGROUND: Based on the excellent results of the clinical trials with ALK-inhibitors, the importance of accurately identifying ALK positive lung cancer has never been greater. However, there are increasing number of recent publications addressing discordances between FISH and IHC. The controversy i...

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Main Authors: Conde, Esther, Suárez-Gauthier, Ana, Benito, Amparo, Garrido, Pilar, García-Campelo, Rosario, Biscuola, Michele, Paz-Ares, Luis, Hardisson, David, de Castro, Javier, Camacho, M. Carmen, Rodriguez-Abreu, Delvys, Abdulkader, Ihab, Ramirez, Josep, Reguart, Noemí, Salido, Marta, Pijuán, Lara, Arriola, Edurne, Sanz, Julián, Folgueras, Victoria, Villanueva, Noemí, Gómez-Román, Javier, Hidalgo, Manuel, López-Ríos, Fernando
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172507/
https://ncbi.nlm.nih.gov/pubmed/25248157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107200
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