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ROS1 copy number alterations are frequent in non-small cell lung cancer

OBJECTIVES: We aimed to determine the prevalence and partners of ROS1 rearrangements, to explore the correlation between FISH and IHC assays, and to investigate clinical implications of ROS1 copy number alterations (CNAs). METHODS: A total of 314 NSCLC patients were screened using ROS1 FISH break-ap...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Clavé, Sergi, Gimeno, Javier, Muñoz-Mármol, Ana M., Vidal, Joana, Reguart, Noemí, Carcereny, Enric, Pijuan, Lara, Menéndez, Sílvia, Taus, Álvaro, Mate, José Luís, Serrano, Sergio, Albanell, Joan, Espinet, Blanca, Arriola, Edurne, Salido, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884972/
https://ncbi.nlm.nih.gov/pubmed/26783962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6921
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