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Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer
INTRODUCTION: Translocation of the anaplastic lymphoma kinase (ALK) gene is involved in the tumorigenesis of a subset of non-small cell lung carcinomas (NSCLCs) and identifies patients sensitive to ALK inhibitors. ALK copy number changes and amplification, which plays an oncogenic role in tumors suc...
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Main Authors: | , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359090/ https://ncbi.nlm.nih.gov/pubmed/21107285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181fb7cd6 |
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