Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer

INTRODUCTION: Translocation of the anaplastic lymphoma kinase (ALK) gene is involved in the tumorigenesis of a subset of non-small cell lung carcinomas (NSCLCs) and identifies patients sensitive to ALK inhibitors. ALK copy number changes and amplification, which plays an oncogenic role in tumors suc...

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Main Authors: Salido, Marta, Pijuan, Lara, Martínez-Avilés, Luz, Galván, Ana B., Cañadas, Israel, Rovira, Ana, Zanui, Montserrat, Martínez, Alejandro, Longarón, Raquel, Sole, Francisco, Serrano, Sergio, Bellosillo, Beatriz, Wynes, Murry W., Albanell, Joan, Hirsch, Fred R., Arriola, Edurne
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359090/
https://ncbi.nlm.nih.gov/pubmed/21107285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181fb7cd6
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