ROS1 copy number alterations are frequent in non-small cell lung cancer

OBJECTIVES: We aimed to determine the prevalence and partners of ROS1 rearrangements, to explore the correlation between FISH and IHC assays, and to investigate clinical implications of ROS1 copy number alterations (CNAs). METHODS: A total of 314 NSCLC patients were screened using ROS1 FISH break-ap...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Clavé, Sergi, Gimeno, Javier, Muñoz-Mármol, Ana M., Vidal, Joana, Reguart, Noemí, Carcereny, Enric, Pijuan, Lara, Menéndez, Sílvia, Taus, Álvaro, Mate, José Luís, Serrano, Sergio, Albanell, Joan, Espinet, Blanca, Arriola, Edurne, Salido, Marta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884972/
https://ncbi.nlm.nih.gov/pubmed/26783962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6921
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