Epithelial Progeny of Estrogen-Exposed Breast Progenitor Cells Display a Cancer-like Methylome

Estrogen imprinting is used to describe a phenomenon in which early developmental exposure to endocrine disruptors increases breast cancer risk later in adult life. We propose that long-lived, self-regenerating stem and progenitor cells are more susceptible to the exposure injury than terminally dif...

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Bibliografiske detaljer
Main Authors: Cheng, Alfred S.L., Culhane, Aedín C., Chan, Michael W.Y., Venkataramu, Chinnambally R., Ehrich, Mathias, Nasir, Aejaz, Rodriguez, Benjamin A.T., Liu, Joseph, Yan, Pearlly S., Quackenbush, John, Nephew, Kenneth P., Yeatman, Timothy J., Huang, Tim H-M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172329/
https://ncbi.nlm.nih.gov/pubmed/18339859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5547
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