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Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue

PURPOSE: Historical data have indicated the potential for the histologically-normal breast to harbor pre-malignant changes at the molecular level. We postulated that a histologically-normal tissue with “tumor-like” gene expression pattern might harbor substantial risk for future cancer development....

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Hlavní autoři: Chen, Dung-Tsa, Nasir, Aejaz, Culhane, Aedin, Venkataramu, Chinnambally, Fulp, William, Rubio, Renee, Wang, Tao, Agrawal, Deepak, McCarthy, Susan M, Gruidl, Mike, Bloom, Gregory, Anderson, Tove, White, Joe, Quackenbush, John, Yeatman, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796276/
https://ncbi.nlm.nih.gov/pubmed/19266279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0344-y
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