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THE PRESENCE OF AN RNA:DNA HYBRID THAT IS PRONE TO SLIPPAGE PROMOTES TERMINATION BY T7 RNA POLYMERASE

Intrinsic termination signals for multisubunit bacterial RNA polymerases (RNAPs) encode a GC-rich stem-loop structure followed by a polyuridine (poly(U)) tract, and it has been proposed that steric clash of the stem-loop with the exit pore of the RNAP imposes a shearing force on the RNA in the downs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Molodtsov, Vadim, Anikin, Michael, McAllister, William T
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172313/
https://ncbi.nlm.nih.gov/pubmed/24976131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.012
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