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THE PRESENCE OF AN RNA:DNA HYBRID THAT IS PRONE TO SLIPPAGE PROMOTES TERMINATION BY T7 RNA POLYMERASE
Intrinsic termination signals for multisubunit bacterial RNA polymerases (RNAPs) encode a GC-rich stem-loop structure followed by a polyuridine (poly(U)) tract, and it has been proposed that steric clash of the stem-loop with the exit pore of the RNAP imposes a shearing force on the RNA in the downs...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172313/ https://ncbi.nlm.nih.gov/pubmed/24976131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.06.012 |
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