Inflammatory Cytokines Drive CD4(+) T-Cell Cycling and Impaired Responsiveness to Interleukin 7: Implications for Immune Failure in HIV Disease

Background. Systemic inflammation has been linked to a failure to normalize CD4(+) T-cell numbers in treated human immunodeficiency virus (HIV) infection. Although inflammatory cytokines such as interleukin 6 (IL-6) are predictors of disease progression in treated HIV infection, it is not clear how...

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Main Authors: Shive, Carey L., Mudd, Joseph C., Funderburg, Nicholas T., Sieg, Scott F., Kyi, Benjamin, Bazdar, Doug A., Mangioni, Davide, Gori, Andrea, Jacobson, Jeffrey M., Brooks, Ari D., Hardacre, Jeffrey, Ammori, John, Estes, Jacob D., Schacker, Timothy W., Rodriguez, Benigno, Lederman, Michael M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172041/
https://ncbi.nlm.nih.gov/pubmed/24585897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu125
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