Inflammatory Cytokines Drive CD4(+) T-Cell Cycling and Impaired Responsiveness to Interleukin 7: Implications for Immune Failure in HIV Disease

Background. Systemic inflammation has been linked to a failure to normalize CD4(+) T-cell numbers in treated human immunodeficiency virus (HIV) infection. Although inflammatory cytokines such as interleukin 6 (IL-6) are predictors of disease progression in treated HIV infection, it is not clear how...

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Detalhes bibliográficos
Main Authors: Shive, Carey L., Mudd, Joseph C., Funderburg, Nicholas T., Sieg, Scott F., Kyi, Benjamin, Bazdar, Doug A., Mangioni, Davide, Gori, Andrea, Jacobson, Jeffrey M., Brooks, Ari D., Hardacre, Jeffrey, Ammori, John, Estes, Jacob D., Schacker, Timothy W., Rodriguez, Benigno, Lederman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172041/
https://ncbi.nlm.nih.gov/pubmed/24585897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu125
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