4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasis

Cancer death is a leading cause of global mortality. An estimated 14.1 million new cancer cases and 8.2 million cancer deaths occurred worldwide in 2012 alone. Cancer stem cells (CSCs) within tumors are essential for tumor metastasis and reoccurrence, the key factors of cancer lethality. Here we rep...

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Main Authors: Yi, Tingfang, Kabha, Eihab, Papadopoulos, Evangelos, Wagner, Gerhard
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2014
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171610/
https://ncbi.nlm.nih.gov/pubmed/25115391
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