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Brachyury cooperates with Wnt/β-catenin signalling to elicit primitive-streak-like behaviour in differentiating mouse embryonic stem cells

BACKGROUND: The formation of the primitive streak is the first visible sign of gastrulation, the process by which the three germ layers are formed from a single epithelium during early development. Embryonic stem cells (ESCs) provide a good system for understanding the molecular and cellular events...

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Hlavní autoři: Turner, David A, Rué, Pau, Mackenzie, Jonathan P, Davies, Eleanor, Martinez Arias, Alfonso
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171571/
https://ncbi.nlm.nih.gov/pubmed/25115237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-014-0063-7
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