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Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

The development of the central nervous system is known to result from two sequential events. First, an inductive event of the mesoderm on the overlying ectoderm that generates a neural plate that, after rolling into a neural tube, acts as the main source of neural progenitors. Second, the axial regi...

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Detalhes bibliográficos
Publicado no:Development
Principais autores: Turner, David A., Hayward, Penelope C., Baillie-Johnson, Peter, Rué, Pau, Broome, Rebecca, Faunes, Fernando, Martinez Arias, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302903/
https://ncbi.nlm.nih.gov/pubmed/25371361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.112979
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