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Wnt/β-catenin and FGF signalling direct the specification and maintenance of a neuromesodermal axial progenitor in ensembles of mouse embryonic stem cells

The development of the central nervous system is known to result from two sequential events. First, an inductive event of the mesoderm on the overlying ectoderm that generates a neural plate that, after rolling into a neural tube, acts as the main source of neural progenitors. Second, the axial regi...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Turner, David A., Hayward, Penelope C., Baillie-Johnson, Peter, Rué, Pau, Broome, Rebecca, Faunes, Fernando, Martinez Arias, Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302903/
https://ncbi.nlm.nih.gov/pubmed/25371361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.112979
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